Andy Robertson could make his 250th Premier League appearance for Liverpool.
Virgil van Dijk, meanwhile, is in line for his 300th Premier League appearance (he made 67 at Southampton). He will be the fourth Dutchman to reach this milestone after George Boateng (384), Dennis Bergkamp (315) and Edwin van der Sar (313).
The Reds are unbeaten in their last 15 matches at Anfield in the month of May (won 11, drawn four) since a 3-1 defeat by Crystal Palace in 2015.
Each of the last two top-flight meetings between the clubs at Anfield have finished level, with the visitors taking the lead inside the opening 10 minutes in both. Never in history has there been three draws in a row in Anfield league clashes.
Liverpool have only drawn more Premier League games with Everton (26) than they have against Arsenal (22).
The Reds have scored 111 Premier League goals against Arsenal – 22 more than the next side (Manchester United, 89).
Since joining Liverpool, Diogo Jota has been involved in more goals versus the Gunners across all competitions than he has against any other team (nine – seven goals and two assists in 11 appearances).
Trent Alexander-Arnold has more Premier League assists against Arsenal than he does versus any other club, with six of his seven assists coming at Anfield. No player in Premier League history has more assists against the Gunners than Alexander-Arnold (level with Steven Gerrard).